CRSP Stock Risk & Deep Value Analysis

CRISPR Therapeutics AG

Healthcare โ€ข Biotechnology

DVR Score

8.6

out of 10

Hidden Gem

The Bottom Line on CRSP

We analyzed CRISPR Therapeutics AG using our deep value framework. Sign in to see our full verdict and DVR Score.

We ran CRSP through our deep value framework โ€” analyzing financial health, distress signals, competitive moat, and risk factors. Here's what we found.

Updated Mar 24, 2026โ€ขRun Fresh Analysis โ†’โ€ข

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CRSP Stock Risk Analysis

Overall Risk

Aggressive

Financial Risk

Medium

Market Risk

Medium

About CRISPR Therapeutics AG (CRSP)

Sector

Healthcare

Industry

Biotechnology

Market Cap Category

mid

Market Cap

$4.44B

CRSP Deep Value Analysis

CRISPR Therapeutics remains a high-potential player in gene editing, positioned for transformative growth. The successful commercialization of Casgevy (with Vertex) and planned pediatric filings in H1 2026 solidify its market entry and de-risk early revenue generation, albeit with a reported ~97.8% YoY revenue decline in an unspecified recent period, indicating challenges in early commercial ramp-up. The recent $550 million convertible notes offering significantly bolsters its balance sheet to $2.56 billion pro forma cash, providing a long runway for its extensive and advancing pipeline in oncology and *in vivo* gene editing. While insider selling and potential dilution from the convertible notes are watch items, and the company remains pre-profitability, its formidable IP, strategic alliance, and first-mover advantage in approved gene therapies sustain its high potential for 10x growth within 3-5 years, despite current commercial execution hurdles.

CRSP Research Sources

Research sources

No external source links for this analysis yet. Run a fresh analysis to capture SEC filings and financial news articles we used.

For educational context only. Not financial advice.

CRSP Red Flags & Warning Signs

  • โš 

    Slower-than-expected CASGEVY commercial ramp-up

  • โš 

    Clinical trial failures or significant delays for pipeline assets

  • โš 

    Increased competition in gene editing space

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CRSP Financial Health Metrics

Market Cap

$4.44B

P/E Ratio

-7.09

Profit Margin

0.00%

Debt-to-Equity

0.11

Dividend Yield

0.00%

Beta (Volatility)

1.72

Earnings Per Share

$-1.37

CRSP Competitive Moat Analysis

Moat Rating

Narrow

Moat Trend

Expanding

Moat Sources

3 Identified

Intangible Assets/IP (CRISPR/Cas9 patent estate)Switching Costs (high development cost, regulatory hurdles, patient-specific nature of gene therapies)First-Mover Advantage (CASGEVY approval)

CRISPR Therapeutics' moat is primarily derived from its foundational IP in gene editing and its early lead in bringing a therapy to market. This creates a significant head start, but patent challenges and emerging alternative technologies could erode its durability over the long term. Continued pipeline success and expansion of indications will strengthen this moat.

CRSP Competitive Moat Analysis

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CRSP Catalysts & Growth Drivers

Near-Term (0-6 months)

  • โ€ขQ1 2026 Earnings on Wednesday, May 6, 2026
  • โ€ขCASGEVY pediatric regulatory filings (H1 2026)
  • โ€ขCTX340 Phase I initiation (H1 2026)

Medium-Term (6-18 months)

  • โ€ขZugo-cel Phase I initiation (H2 2026)
  • โ€ขCTX460 Phase I initiation (mid-2026)
  • โ€ขInitial CASGEVY pediatric approvals and market launch

Long-Term (18+ months)

  • โ€ขExpansion of CASGEVY into additional indications or geographies
  • โ€ขMultiple new product approvals from diverse pipeline assets
  • โ€ขIndustry leadership in *in vivo* gene editing therapies

Catalysts & Growth Drivers

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CRSP Bull Case: What Could Go Right

  • โœ“

    Acceleration in CASGEVY patient enrollment and revenue figures

  • โœ“

    Positive clinical trial data for CTX programs, especially in oncology and *in vivo* applications

  • โœ“

    New strategic partnerships or major milestone payments

Bull Case Analysis

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FAQ

What is the DVR Score for CRISPR Therapeutics AG (CRSP)?

As of March 24, 2026, CRISPR Therapeutics AG has a DVR Score of 8.6 out of 10, placing it in the "Hidden Gem" category. This score is generated by our AI-powered deep value analysis framework that evaluates growth potential, financial health, competitive moat, and risk factors.

What is the market capitalization of CRISPR Therapeutics AG?

CRISPR Therapeutics AG's market capitalization is approximately $4.4B. The company operates in the Healthcare sector within the Biotechnology industry.

What ticker symbol does CRISPR Therapeutics AG use?

CRSP is the ticker symbol for CRISPR Therapeutics AG. The company trades on the NGM.

What is the risk level for CRSP stock?

Our analysis rates CRISPR Therapeutics AG's overall risk as Aggressive. This assessment considers execution risk, market risk, financial risk, competitive risk, and regulatory risk. For a full breakdown, see the risk analysis section above.

What is the P/E ratio of CRSP?

CRISPR Therapeutics AG currently has a price-to-earnings (P/E) ratio of -7.1. This is below the market average, which could indicate the stock is undervalued or facing headwinds.

Is CRISPR Therapeutics AG's revenue growing?

CRISPR Therapeutics AG has reported revenue growth of -97.6%. Revenue has been declining, which warrants closer examination.

Is CRSP stock profitable?

CRISPR Therapeutics AG has a profit margin of 0.0%. The company is currently unprofitable.

How often is the CRSP DVR analysis updated?

Our AI-powered analysis of CRISPR Therapeutics AG is refreshed regularly to incorporate the latest financial data, market conditions, and news. The most recent update was on March 24, 2026.

Important Disclaimer โ€“ Not Financial Advice

Deep Value Reports is an independent research platform for educational and informational purposes only. We are not financial advisors, investment advisors, or licensed professionals. The analysis, scores, and information provided should not be construed as personalized investment advice, a recommendation to buy or sell any security, or an offer to provide investment advisory services.

All investments involve risk, including the potential loss of principal. Past performance does not guarantee future results. Always conduct your own research and consult with a qualified financial advisor.