PPBT Stock Risk & Deep Value Analysis

Purple Biotech Ltd

Healthcare • Biotechnology

DVR Score

5.6

out of 10

Proceed with Caution

What You Need to Know About PPBT Stock

We analyzed Purple Biotech Ltd using our deep value framework. Sign in to see our full verdict and DVR Score.

We ran PPBT through our deep value framework — analyzing financial health, distress signals, competitive moat, and risk factors. Our risk assessment: Aggressive. Here's what we found.

Updated Mar 1, 2026Run Fresh Analysis →

How Risky Is PPBT Stock?

Overall Risk

Aggressive

Financial Risk

High

Market Risk

Medium

Competitive Risk

Medium

Execution Risk

High

Regulatory Risk

High

What Are the Red Flags for PPBT?

  • Failure to secure sufficient funding leading to delisting or bankruptcy

  • Negative or inconclusive clinical trial results

  • Significant further dilution impacting shareholder value

  • Competitive advancements from rival oncology treatments

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What Does Purple Biotech Ltd (PPBT) Do?

Market Cap

$7.33M

Sector

Healthcare

Industry

Biotechnology

Employees

9

Purple Biotech Ltd., a clinical-stage company, focuses on developing therapies to overcome tumor immune evasion and drug resistance for cancer patients in the United States. Its oncology pipeline includes CM24, a humanized monoclonal antibody that blocks the interactions of carcinoembryonic antigen related cell adhesion molecule 1 as a combination therapy with anti-PD-1 checkpoint inhibitors, which is in Phase 2 clinical trial for the treatment of pancreatic ductal adenocarcinoma; NT219, a small molecule that targets and inhibits insulin receptor substrate 1 and 2, and signal transducer and activator of transcription, which is in Phase 1/2 clinical trials for the treatment recurrent and/or metastatic squamous cell carcinoma of the head and neck cancer or colorectal adenocarcinoma; and IM1240, a multi-valent antibody designed to activate anti-tumoral immune response against 5T4-positive tumors, which is in preclinical stage. The company has collaboration agreement with Bristol Myers Squibb Company to evaluate the combination of CM24 with the PD-1 inhibitor nivolumab in addition to chemotherapy. The company was formerly known as Kitov Pharma Ltd and changed its name to Purple Biotech Ltd. in December 2020. The company was incorporated in 1968 and is headquartered in Rehovot, Israel.

Visit Purple Biotech Ltd Website

Is PPBT Stock Undervalued?

Purple Biotech continues to target high-unmet-need oncology markets with promising mid-stage assets (CM24, NT219) for pancreatic cancer and NSCLC, indicating substantial TAM and significant 10x potential upon clinical success (high score for Market Opportunity). Leadership possesses relevant biotech experience. However, the critical red flag of an extremely tight cash runway, highlighted previously, has become even more severe with the passage of 41 days without a resolution. This significantly increases the probability of highly dilutive financing, severely impacting the path to 10x returns for existing shareholders without a major non-dilutive partnership or funding event. While scientific promise remains, the exacerbated financial fragility introduces extreme risk, warranting a slight reduction in the overall score. **Score Change Explanation:** The score has been adjusted from 58 to 56, a decrease of 2 points. This adjustment is due to the continued deterioration of the company's financial health since the last analysis on 2026-01-19. With 41 additional days having passed without a reported resolution to the critical cash runway issue, the urgency and probability of highly dilutive financing have increased, directly eroding the potential for 10x returns for existing shareholders. This exacerbation of financial risk justifies the slight downward revision.

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Does PPBT Have a Competitive Moat?

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Moat Rating

🛡️ Narrow

Moat Trend

Eroding

Moat Sources

1 Identified

Intangible Assets/IP

The moat is derived from the patented drug candidates (CM24, NT219). Its durability is severely compromised by the company's financial distress. Without sufficient funding to advance trials and defend IP, the value of these assets, and thus the moat, rapidly diminishes.

Moat Erosion Risks

  • Inability to fund and complete clinical trials
  • Expiration of patents or invalidation by competitors
  • Failure to secure partnerships to de-risk development

PPBT Competitive Moat Analysis

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What Could Drive PPBT Stock Higher?

Near-Term (0-6 months)

  • Announcement of new funding (dilutive or non-dilutive) - *CRITICAL*
  • Clinical trial updates for CM24 (Pancreatic Cancer) or NT219 (NSCLC)

Medium-Term (6-18 months)

  • Potential strategic partnership or licensing agreement
  • Advancement of lead candidates into later-stage trials

Long-Term (18+ months)

  • Regulatory approval and commercialization of CM24 or NT219
  • Expansion of pipeline through M&A or in-licensing

Catalysts & Growth Drivers

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What's the Bull Case for PPBT?

  • Announcement of significant non-dilutive funding or major partnership

  • Positive Phase 2/3 clinical trial readouts for CM24 or NT219

  • Insider buying activity (signaling conviction in a turnaround)

Bull Case Analysis

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Important Disclaimer – Not Financial Advice

Deep Value Reports is an independent research platform for educational and informational purposes only. We are not financial advisors, investment advisors, or licensed professionals. The analysis, scores, and information provided on this page for PPBT (Purple Biotech Ltd) should not be construed as personalized investment advice, a recommendation to buy or sell any security, or an offer to provide investment advisory services.

All investments involve risk, including the potential loss of principal. Past performance does not guarantee future results. Always conduct your own research, consider your financial situation, and consult with a qualified financial advisor before making any investment decisions.

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